|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Tested Species reactivity||Mouse|
|Host / Isotype||Armenian hamster / IgG|
|Immunogen||KLH conjugated mouse zeta-chain (CD3) sequence 151-164|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17672 targets CD247/CD3z in FACS and IF applications and shows reactivity with Mouse samples.
The MA5-17672 immunogen is kLH conjugated mouse zeta-chain (CD3) sequence 151-164.
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD247; CD247 antigen; CD3 antigen, zeta polypeptide; CD3-ZETA; CD3-zeta/eta; CD3H; CD3Q; T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain; T-cell surface glycoprotein CD3 zeta chain; T3Z; TCRZ
Gene Aliases: 4930549J05Rik; A430104F18Rik; AW552088; Cd247; Cd3; Cd3-eta; Cd3-zeta; Cd3h; Cd3z; Cd3zeta; T3z; Tcrk; Tcrz
UniProt ID: (Mouse) P24161
Entrez Gene ID: (Mouse) 12503
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.