|Flow Cytometry (Flow)||1:10 - 1:50|
|Tested Species reactivity||Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Spleen cells from B6PL-Ly-2a / Ly-3a B6-Ly-1a mice.|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred, store in dark|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD44; CD44 antigen; Cell surface glycoprotein CD44; ECMR-III; Extracellular matrix receptor III; GP90 lymphocyte homing adhesion receptor; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; HUTCH-I; hyaluronate binding protein; Hyaluronate receptor; Ly-24; Lymphocyte antigen 24; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I
Gene Aliases: AU023126; AW121933; AW146109; Cd44; HERMES; Ly-24; Pgp-1
UniProt ID: (Mouse) P15379
Entrez Gene ID: (Mouse) 12505
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.