|Flow Cytometry (Flow)||3-5 µg/10^6 cells|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rat / IgG1, kappa|
|Immunogen||Mouse lymph node cells.|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-70096 detects CD45 in mouse samples.
MA1-70096 has been successfully used in flow cytometry, immunohistochemistry (frozen sections) and immunoprecipitation procedures.
The MA1-70096 immunogen is mouse lymph node cells.
CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B220; c polypeptide; CD45 antigen; CD45R; GP180; LCA; leukocyte common antigen; LY5; lymphocyte antigen 5; lymphocyte common antigen; protein tyrosine phosphatase; receptor type; receptor-type tyrosine-protein phosphatase C; T200 glycoprotein; T200 leukocyte common antigen
Gene Aliases: B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4; T200
Entrez Gene ID: (Mouse) 19264
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