|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Stimulated human leucocytes.|
|Storage buffer||PBS, pH 7.6, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
A suggested positive control is tonsil tissue.
CD45 or Leukocyte Common Antigen (LCA/T200) is a membrane sialoglycoproteins with three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates various isoforms. CD45RA.is a single chain glycoprotein. It is expressed on appoximately 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. CD45RA are naive or virgin T-cells while, T-cells expressing CD45RO are memory T-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B220; CD45; CD45 antigen; CD45R; GP180; L-CA; LCA; Leukocyte common antigen; LY5; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Aliases: B220; CD45; CD45R; GP180; L-CA; LCA; LY5; PTPRC; T200
UniProt ID: (Human) P08575
Entrez Gene ID: (Human) 5788
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