|Flow Cytometry (Flow)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1/IgG2a|
|Immunogen||T-acute lymphoblastic leukemia (T-ALL) cells|
|Conjugate||FITC , PE|
|Storage buffer||PBS with 0.2% carrier protein|
|Contains||0.08% sodium azide|
|Storage conditions||4° C, do not freeze|
This antibody is a monoclonal mixture of FITC-conjugated CD7 (clone MG34, isotype IgG2a) and PE-conjugated CD13 (clone E735, isotype IgG1).
CD7 is a 40kD transmembrane, single-chain glycoprotein. CD7 is expressed by majority of peripheral blood T cells, NK cells and all Thymocytes. The presence or absence of CD7 is a useful marker for the classification of T- and NK-cell malignancies. The CD7 molecule is absent in a subset of human T cells under certain physiologic conditions. Thus an increase in CD7 negative T cells can be seen in some inflammatory skin disease. This antibody recognizes the human CD13 cell surface glycoprotein, a 150kD molecule expressed by granulocytes and monocytes, and by myeloid leukemia cells. Inhibits infection of cells by human coronavirus, inhibits aminopeptidase N activity of the CD13 molecule immunoprecipitates. MA1-22542 detects CD13 in Human samples.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alanyl (membrane) aminopeptidase; Alanyl aminopeptidase; Aminopeptidase M; Aminopeptidase N; aminopeptidase N/CD13; ANPEP; AP-M; AP-N; Apn; CD13; CD7; CD7 antigen (p41); gp150; GP40; hAPN; LEU-9; membrane alanyl aminopeptidase; membrane protein p161; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
Gene Aliases: ANPEP; APN; CD13; CD7; GP150; GP40; LAP1; LEU-9; P150; PEPN; Tp40; TP41
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