|Flow Cytometry (Flow)||Neat - 1/10|
|Tested Species reactivity||Bovine, Goat, Sheep|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Ovine efferent lymphocytes.|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred, store in dark|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: CD8; CD8 antigen, alpha polypeptide (p32); CD8a; CD8a molecule; CD8alpha; CD8beta; Leu-2; MAL; T-cell surface glycoprotein CD8 alpha chain
Gene Aliases: BOS_11616; CD8A
UniProt ID: (Bovine) P31783
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