|Flow Cytometry (Flow)||1:100|
|Immunohistochemistry (Frozen) (IHC (F))||1:50|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS, pH 7.2|
|Contains||0.01% sodium azide|
|Storage conditions||4°C or -80°C if preferred|
MA1-7632 detects CD8 from human, rat and mouse samples.
MA1-7632 has been successfully used in ELISA, flow cytometry, immunoprecipitation, and immunohistochemistry (frozen sections) procedures.
The MA1-7632 immunogen is a CD8 protein.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD8; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha-chain; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8a; CD8alpha; CD8b; CD8beta; Leu-2; Leu2 T-lymphocyte antigen; Lymphocyte antigen 3; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); MAL; OKT8 T-cell antigen; OX-8 membrane antigen; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-lymphocyte differentiation antigen T8/Leu-2; T8 T-cell antigen
Gene Aliases: BB154331; CD8; CD8A; CD8B; CD8B1; LEU2; Ly-2; Ly-3; Ly-35; Ly-B; Ly-C; LY3; Lyt-2; Lyt-3; Lyt2; LYT3; MAL; p32; P37
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