|Flow Cytometry (Flow)||Neat-1:10|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Mouse|
|Published species reactivity||Human|
|Host / Isotype||Rat / IgG2a|
|Immunogen||T cell clone, C6|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred, store in dark|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD8 is expressed on T-cells and exists either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. CD8 functions as a co-receptor with the T-cell receptor and mediates efficient cel-to-cell interactions within the immune system. The CD8 alpha chain specifically binds to class I MHC molecules. CD8 alpha is expressed by a subset of T lymphocytes, most thymocytes, and the majority of NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD8; CD8a; Leu-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); MAL; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein Lyt-2
Gene Aliases: BB154331; Cd8a; Ly-2; Ly-35; Ly-B; Lyt-2; Lyt2
UniProt ID: (Mouse) P01731
Entrez Gene ID: (Mouse) 12525
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