|Flow Cytometry (Flow)||0.1-0.2 ug per 1x10^6 cells|
|Tested Species reactivity||Mouse|
|Host / Isotype||Armenian hamster / IgG, kappa|
|Immunogen||Mouse CD81 (TAPA-1).|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 26 kDa cell surface protein TAPA-1; CD81; CD81 antigen; target of antiproliferative antibody 1; Target of the antiproliferative antibody 1; tetraspanin-28; tspan-28
Gene Aliases: Cd81; Tapa-1; Tapa1; Tspan28
UniProt ID: (Mouse) P35762
Entrez Gene ID: (Mouse) 12520
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