|Flow Cytometry (Flow)||Neat|
|Immunocytochemistry (ICC)||See 1 publications below|
|Flow Cytometry (Flow)||See 2 publications below|
|Miscellaneous PubMed (MISC)||See 4 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human peripheral blood lymphocytes.|
|Storage buffer||PBS, pH 7.2, with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred, store in dark|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activation B7-2 antigen; B-lymphocyte activation antigen B7-2; B-lymphocyte antigen B7-2; B7-2; B7-2 antigen; B7.2; B70; BU63; CD28 antigen ligand 2; CD28LG2; CD86; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CTLA-4 counter-receptor B7.2; FUN-1; LAB72; MGC34413; T-lymphocyte activation antigen CD86
Gene Aliases: B7-2; B7.2; B70; CD28LG2; CD86; LAB72
UniProt ID: (Human) P42081
Entrez Gene ID: (Human) 942
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