|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 288 of Human CDC25C|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27790 targets CDC25C in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27790 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 288 of Human CDC25C.
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC25; cell division cycle 25C; Dual specificity phosphatase Cdc25C; M-phase inducer phosphatase 3; mitosis inducer CDC25; phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1; protein phosphatase 1, regulatory subunit 60; regulatory subunit 60
Gene Aliases: CDC25; CDC25C; PPP1R60
UniProt ID: (Human) P30307
Entrez Gene ID: (Human) 995
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