|Western Blot (WB)||0.5-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ERRGHLRPSFHG) corresponding to the internal amino acids of CDH11|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAD11; cadherin 11, type 2; cadherin 11, type 2, OB-cadherin (osteoblast); Cadherin-11; CDH11; CDHOB; OB; OB-cadherin; OSF-4; Osteoblast cadherin
Gene Aliases: CAD11; CDH11; CDHOB; OB; OSF-4
UniProt ID: (Human) P55287
Entrez Gene ID: (Human) 1009
Molecular Function: cadherin
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