|Flow Cytometry (Flow)||2-4 µg/10^6 cells|
|Immunoprecipitation (IP)||5 µg|
|Western Blot (WB)||1:2000|
|Western Blot (WB)||See 14 publications below|
|Immunohistochemistry (IHC)||See 3 publications below|
|Miscellaneous PubMed (MISC)||See 8 publications below|
|Immunofluorescence (IF)||See 1 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Immunohistochemistry (Frozen) (IHC (F))||See 1 publications below|
|Immunocytochemistry (ICC)||See 2 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Pig , Rat , Bovine , Human , Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant protein derived from an intracellular sequence of the human Cadherin 11 protein.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cadherin 11; cadherin 11, type 2, OB-cadherin (osteoblast); Cadherin-11; OB Cadherin; OB-cadherin; OSF-4; Osteoblast Cadherin; osteoblast-cadherin
Gene Aliases: Cad-11; CAD11; CDH11; CDHOB; OB; OSF-4
Molecular Function: cadherin
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