|Flow Cytometry (Flow)||Assay-Dependent|
|Immunohistochemistry (IHC)||5-10 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||5-10 µg/ml|
|Western Blot (WB)||2 µg/ml|
|Tested Species reactivity||Bovine, Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to a C-terminal region of the human CDR2 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris citrate, pH 7-8|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
This antibody shares 85% sequence homology with rat.
Suggested positive control: Hela whole cell extract, antigen standard for CDR2 (transient overexpression lysate).
Using anti-Yo antibodies, three genes have been cloned (CDR 1-3). CDR2 suppresses the transcriptional activity and DNA binding of nuclear factor-kappa B by an unknown mechanism. The neuron specific expression of CDR2 is regulated by a post-transcriptional mechanism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cerebellar degeneration-related antigen-2; cerebellar degeneration-related protein (62kD); Cerebellar degeneration-related protein 2; cerebellar degeneration-related protein 2, 62kDa; major Yo paraneoplastic antigen; paraneoplastic cerebellar degeneration-associated antigen; Yo paraneoplastic antigen
Gene Aliases: AA617262; BOS_22763; Cdr2; CDR62; Yo
UniProt ID: (Mouse) P97817
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