|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ARLAHQTRAEEGL) corresponding to the C-terminus amino acids of CDT1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDT1; chromatin licensing and DNA replication factor 1; DNA replication factor Cdt1; DNA replication factor, Double parked, Drosophila, homolog of; Double parked; Double parked homolog; Double parked, Drosophila, homolog of; DUP; RIS2
Gene Aliases: CDT1; DUP; RIS2
UniProt ID: (Human) Q9H211
Entrez Gene ID: (Human) 81620
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