|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human CEA expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15800 targets CEA in IHC and WB applications and shows reactivity with Human samples.
The MA5-15800 immunogen is purified recombinant fragment of human CEA expressed in E. Coli.
MA5-15800 detects CEA which has a predicted molecular weight of approximately 77kDa.
Carcino Embryonic Antigen (CEA) is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).The carcinoembryonic antigen (CEA) is a member of a large family of glycoproteins and a useful tumor marker for adenocarcinoma.Tissue specificity: Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Carcinoembryonic Antigen; Carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CEA; Meconium antigen 100
Gene Aliases: CD66e; CEA; CEACAM5
UniProt ID: (Human) P06731
Entrez Gene ID: (Human) 1048
Molecular Function: G-protein coupled receptor cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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