|Immunocytochemistry (ICC)||10 µg/ml|
|Immunofluorescence (IF)||10 ug/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Western Blot (WB)||1 µg/ml|
|Tested Species reactivity||Chicken, Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide corresponding to residues P(3) R R R S R K P E A P R R R S P S(19) of human CENPA protein.|
|Storage buffer||PBS, pH 7.2, with 50% glycerol|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-20832 detects CENPA in human and chicken samples. This antibody does not cross react with mouse or rat CENPA proteins.
MA1-20832 has been successfully used in immunocytochemistry, neutralization, immunohistochemistry and Western blot procedures.
The MA1-20832 immunogen corresponds to synthetic peptide corresponding to residues P(3) R R R S R K P E A P R R R S P S(19) of human CENPA protein.
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CENP-A; Centromere autoantigen A; Centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; Histone H3-like centromeric protein A
Gene Aliases: CenH3; CENP-A; CENPA
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.