|Western Blot (WB)||0.5 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 200-300 of human CG158.|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Suggested positive control: antigen standard for ABHD5 (transient overexpression lysate), human skeletal muscle protein.
The CGI-58 protein belongs to a large family of proteins characterized by an alpha/beta hydrolase fold. CGI-58 protein is involved in the lipid metabolism of lamellar granules. Defective lipid production in lamellar granules, caused by a CGI-58 protein deficiency, is involved in the pathogenesis of ichthyosis in Dorfman–Chanarin syndrome. Dorfman–Chanarin syndrome is a rare autosomal recessive inherited lipid storage disease characterized by the presence of intracellular lipid droplets in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; ABHD5; Abhydrolase domain-containing protein 5; CGI 58; CGI-58; Lipid droplet-binding protein CGI-58; Protein CGI-58; truncated abhydrolase domain-containing protein 5
Gene Aliases: 1300003D03Rik; 2010002J10Rik; ABHD5; CDS; CGI-58; CGI58; IECN2; IECN5; NCIE2
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