|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 260 and 476 of Human CHD-2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29491 targets CHD-2 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29491 immunogen is recombinant fragment corresponding to a region within amino acids 260 and 476 of Human CHD-2.
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent helicase CHD2; CHD-2; Chromodomain-helicase-DNA-binding protein 2
Gene Aliases: CHD2; EEOC
UniProt ID: (Human) O14647
Entrez Gene ID: (Human) 1106
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