|Immunohistochemistry (Paraffin) (IHC (P))||6 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CHRM5.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon (94%) Chimpanzee, Marmoset (88%) Dog, Bovine, Panda, Horse (81%).
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acetylcholine receptor, muscarinic 5; cholinergic receptor, muscarinic 5; CHRM5; HM5; M5 muscarinic receptor; Muscarinic acetylcholine receptor M5; Muscarinic m5 receptor; Muscarinic receptor M5
Gene Aliases: CHRM5; HM5
UniProt ID: (Human) P08912
Entrez Gene ID: (Human) 1133
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