|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 203 and 420 of Human CHST15|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31727 targets CHST15 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31727 immunogen is recombinant fragment corresponding to a region within amino acids 203 and 420 of Human CHST15.
Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B cell RAG associated protein (GALNAC4S-6ST); B-cell RAG-associated gene protein; BRAG; Carbohydrate sulfotransferase 15; GALNAC4S-6ST; hBRAG; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase; RP11-47G11.1
Gene Aliases: BRAG; CHST15; GALNAC4S-6ST; GALNAC4S6ST; KIAA0598
UniProt ID: (Human) Q7LFX5
Entrez Gene ID: (Human) 51363
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