|Western Blot (WB)||0.1-0.3 ug/ml|
|Tested Species reactivity||Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (NYRRTDHEDPRVK) corresponding to the internal amino acids of CILP|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine, human and mouse based on sequence homology.
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cartilage intermediate layer protein; cartilage intermediate layer protein 1; cartilage intermediate layer protein, nucleotide pyrophosphohydrolase; CILP; HGNC:1980; HsT18872
Entrez Gene ID: (Rat) 315761
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