|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Clone||3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11|
|Immunogen||Purified recombinant fragment of CK1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15300 targets CK1 in IHC and WB applications and shows reactivity with Human samples.
The MA5-15300 immunogen is purified recombinant fragment of CK1 expressed in E. Coli.
CK1 (also designated Cytokeratin 1 or KRT1 ),with 644-amino acid protein (about 70kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: casein kinase 1, alpha 1; Casein kinase I isoform alpha; CK1; CKI-alpha; clock regulator kinase; CSNK1A1; down-regulated in lung cancer; epididymis secretory sperm binding protein Li 77p; HLCDGP1; PRO2975
Gene Aliases: CK1; CK1a; CKIa; CSNK1A1; HEL-S-77p; HLCDGP1; PRO2975
UniProt ID: (Human) P48729
Entrez Gene ID: (Human) 1452
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