|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 350 of Human CKII alpha|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29185 targets CKII alpha in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-29185 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 350 of Human CKII alpha.
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: casein kinase 2 alpha'; casein kinase 2, alpha 1 polypeptide; casein kinase 2, alpha prime polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; Casein kinase II subunit alpha; Casein kinase II subunit alpha'; CK II alpha; CK II alpha 3; CK II alpha'; CK2 catalytic subunit alpha; CK2A2; CSNK2A1; protein kinase CK2
Gene Aliases: CK2A1; CK2A2; CK2alpha'; CKII; CSNK2A1; CSNK2A2; CSNK2A3
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