|Western Blot (WB)||1:500 - 1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic Peptide corresponding to the N-terminal sequence M N F I K D N S R A L I Q R M G M|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
PA1-4264 detects CLAN protein from human samples. This antibody detects both A and B isoforms.
PA1-4264 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~116 kDa protein representing CLAN-A and a ~43 kDa protein representing CLAN-B in lung lysate.
PA1-4264 immunizing peptide corresponds to N-terminal sequence M N F I K D N S R A L I Q R M G M.
A novel human CED-4-like gene, CLAN, is a caspase-associated recruitment domain (CARD)-containing proteins and is expressed at varying degrees in normal human tissues. It contributes to a number of intracellular processes including apoptosis, cytokine processing, and NF-kappa B activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: and NACHT-containing protein; CARD; CARD, LRR, and NACHT-containing protein; caspase recruitment domain family, member 12; Caspase recruitment domain-containing protein 12; Clan protein; Ice protease-activating factor; ICE-protease activating factor; Ipaf; LRR; NLR family CARD domain-containing protein 4; NLR family, CARD domain containing 4; NOD-like receptor C4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
Gene Aliases: AIFEC; CARD12; CLAN; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; IPAF; NLRC4; UNQ6189/PRO20215
UniProt ID: (Human) Q9NPP4
Entrez Gene ID: (Human) 58484
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