|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment contains a sequence corresponding to a region within amino acids 1 and 218 of CLEC5A|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-34928 targets CLEC5A in WB applications and shows reactivity with Human samples.
The PA5-34928 immunogen is recombinant protein fragment contains a sequence corresponding to a region within amino acids 1 and 218 of CLEC5A.
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation . Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; C-type calcium dependent; C-type lectin domain family 5 member A; C-type lectin domain family 5, member A; C-type lectin superfamily member 5; carbohydrate-recognition domain; CLECSF5; MDL-1; MDL1; Myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; superfamily member 5
Gene Aliases: CLEC5A; CLECSF5; MDL-1; MDL1
UniProt ID: (Human) Q9NY25
Entrez Gene ID: (Human) 23601
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