|Immunohistochemistry (Paraffin) (IHC (P))||1:50|
|Western Blot (WB)||Assay-Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to KLH derived from within residues 550 - 650 of Human CLLD8/SETDB2.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-19436 targets CLLD8/SETDB2 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-19436 immunogen is synthetic peptide conjugated to KLH derived from within residues 550 - 650 of Human CLLD8/SETDB2.
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C13orf4, CLLD8, CLLL8, DKFZp586I0123, DKFZp761J1217, KMT1F, chronic lymphocytic leukemia deletion region 8; Chronic lymphocytic leukemia deletion region gene 8 protein; Histone-lysine N-methyltransferase SETDB2; Lysine N-methyltransferase 1F; SET domain bifurcated 2
Gene Aliases: C13orf4; CLLD8; CLLL8; KMT1F; SETDB2
UniProt ID: (Human) Q96T68
Entrez Gene ID: (Human) 83852
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