|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human CNO6L|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and Xenopus based on sequence homology.
CNO6L plays a role in the deadenylation of mRNAs in the cytoplasm. CNO6L has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. CNO6L may be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. This protein involved in deadenylation-dependent degradation of CDKN1B mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Carbon catabolite repressor protein 4 homolog B; CCR4-NOT transcription complex subunit 6-like; CCR4-NOT transcription complex, subunit 6-like; CCR4b
Gene Aliases: CCR4B; CNOT6L
UniProt ID: (Human) Q96LI5
Entrez Gene ID: (Human) 246175
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