|ELISA (ELISA)||0.5 - 2 µg/ml|
|Functional Assay (FN)||7-11 ug/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||0.25 ug/ml|
|Western Blot (WB)||0.1 - 0.2 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant human CNTF|
|Storage buffer||PBS, pH 7.2|
|Storage conditions||4° C|
Reconstitute with 0.1 ml of distilled water. Prior to reconstitution, store at 4°C. After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles.
This antibody may be used in Western Blotting applications under either reducing or non-reducing conditions.
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ciliary neurotrophic factor; CNTF; HCNTF
Gene Aliases: CNTF; HCNTF
UniProt ID: (Human) P26441
Entrez Gene ID: (Human) 1270
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