|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 206 of Human COBRA1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27602 targets COBRA1 in IF and WB applications and shows reactivity with Human samples.
The PA5-27602 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 206 of Human COBRA1.
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cofactor of BRCA1; Negative elongation factor B; negative elongation factor complex member B, Cobra1; negative elongation factor protein B; NELF-B; NELFB; ortholog of human cofactor of BRCA1 (COBRA1)
Gene Aliases: A730008L03Rik; AB041607; AI663983; COBRA1; KIAA1182; MNCb-5210; NELF-B; NELFB
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