|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 217 of Human COG2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30710 targets COG2 in WB applications and shows reactivity with Human samples.
The PA5-30710 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 217 of Human COG2.
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: brefeldin A-sensitive; brefeldin A-sensitive, peripheral Golgi protein; COG complex subunit 2; Component of oligomeric Golgi complex 2; conserved oligomeric Golgi complex protein 2; Conserved oligomeric Golgi complex subunit 2; LDLC; low density lipoprotein receptor defect; low density lipoprotein receptor defect C complementing; Low density lipoprotein receptor defect C-complementing protein; peripheral Golgi protein
Gene Aliases: COG2; LDLC
UniProt ID: (Human) Q14746
Entrez Gene ID: (Human) 22796
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