|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 571-599 amino acids from the C-terminal region of human COL8A2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COL8A2; Collagen alpha-2(VIII) chain; collagen VIII, alpha-2 polypeptide; collagen, type VIII, alpha 2; Endothelial collagen
Gene Aliases: COL8A2; FECD; FECD1; PPCD; PPCD2
UniProt ID: (Human) P25067
Entrez Gene ID: (Human) 1296
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