|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 452 and 693 of Human CPSF2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31004 targets CPSF2 in WB applications and shows reactivity with Human and mouse samples.
The PA5-31004 immunogen is recombinant protein fragment corresponding to a region within amino acids 452 and 693 of Human CPSF2.
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
Protein Aliases: cleavage and polyadenylation specific factor 2, 100kD subunit; cleavage and polyadenylation specific factor 2, 100kDa; Cleavage and polyadenylation specificity factor 100 kDa subunit; Cleavage and polyadenylation specificity factor subunit 2; CPSF 100 kDa subunit; CPSF 100kDa subunit; CPSF100
Gene Aliases: 100kDa; 2610024B04Rik; AI662483; Cpsf; CPSF100; CPSF2; KIAA1367; MCPSF; mKIAA1367