|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (LETLKDICSPKTDY) corresponding to the C-terminus amino acids of CREM|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cAMP response element modulator; cAMP responsive element modulator; cAMP-responsive element modulator; CREM; CREM 2alpha-b protein; CREM 2beta-a protein; hCREM 2alpha-b protein; hCREM 2beta-a protein; hCREM-2; ICER; Inducible cAMP early repressor; inducible cAMP early repressor ICER; MGC111110; MGC17881; MGC41893; OTTHUMP00000019442; OTTHUMP00000019443
Gene Aliases: CREM; CREM-2; hCREM-2; ICER
UniProt ID: (Human) Q96AG7
Entrez Gene ID: (Human) 1390
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