|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CRF-RII|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28755 targets CRF-RII in WB applications and shows reactivity with Human samples.
The PA5-28755 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CRF-RII.
Liaw et al. (1996) [PubMed 8536644] stated that there are 2 G protein-coupled corticotropin-releasing hormone (CRH; MIM 122560) receptors, CRHR1 (MIM 122561) and CRHR2, which they termed the CRF2 receptor. CRH is a 41-amino acid peptide synthesized in the hypothalamus that is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: beta isoform; Corticotropin-releasing factor receptor 2; Corticotropin-releasing hormone receptor 2; CRF-R-2; CRF2; CRF2 receptor; CRF2 receptor, beta isoform; CRFR2; CRH receptor 2 variant B; CRH-R-2; CRH-R2; HM-CRF
Gene Aliases: CRF-RB; CRF2; CRF2R; CRFR2; CRH2R; CRHR2; HM-CRF
UniProt ID: (Human) Q13324
Entrez Gene ID: (Human) 1395
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