|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Western Blot (WB)||0.1-0.3 ug/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (NEEKKSKVHYH) corresponding to the internal amino acids of CRHR1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with rat based on sequence homology.
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neighboring gene MGC57346.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: corticotropin releasing hormone receptor 1; corticotropin releasing hormone receptor variant 1h; Corticotropin-releasing factor receptor 1; corticotropin-releasing factor type 1 receptor; Corticotropin-releasing hormone receptor 1; CRF 1 receptor; CRF-R; CRF-R-1; CRF-R1; CRF-R1alpha; CRFR-1; CRFR1; CRH receptor 1; CRH receptor subtype-1 isoform-3; CRH-R-1; CRH-R1; CRH-R1h; CRHR; CRHR1; CRHR1f; seven transmembrane helix receptor
Gene Aliases: CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; Crhr1; CRHR1L
UniProt ID: (Mouse) P35347
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