|Flow Cytometry (Flow)||Assay Dependent|
|Tested Species reactivity||Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified rCTLA-4hlg fusion protein|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17584 targets CD152/CTLA4 in FACS applications and shows reactivity with Rat samples.
The MA5-17584 immunogen is purified rCTLA-4hlg fusion protein.
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD152 antigen; CD152 isoform; celiac disease 3; CELIAC3; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte antigen 4; cytotoxic T-lymphocyte protein 4; GRD4; GSE; ICOS; IDDM12; soluble form; transmembrane form
Gene Aliases: Cd152; CTLA-4; sCTLA4
Entrez Gene ID: (Rat) 63835
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