|Flow Cytometry (Flow)||Assay-Dependent|
|Western Blot (WB)||1:2000|
|Tested Species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant full length protein (Rat).|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-22486 detects CXCR4 in mouse and rat samples.
PA1-22486 has been successfully used in Western blot procedures.
PA1-22486 immunogen is recombinant full length protein (rat).
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°Cor below. Avoid freeze-thaw cycles.
CXCR4 (fusin) is one of the members in the seven-transmembrane G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library. Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been proved to be the co-receptor forHIV-2's binding to CD4 through envelope glycoprotein gp 120. In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-X-C chemokine receptor type 4; CD184; chemokine (C-X-C) receptor 4; chemokine receptor (LCR1); chemokine receptor 4; CXC chemokine receptor; CXC Chemokine Receptor 4; CXC-R4; CXCR-4; Fusin; HUMSTR; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; PB-CKR; Pre-B-cell-derived chemokine receptor; SDF-1 receptor; Stromal cell-derived factor 1 receptor
Gene Aliases: b2b220Clo; CD184; Cmkar4; Cxcr4; LESTR; PB-CKR; PBSF/SDF-1; Sdf1r
UniProt ID: (Mouse) P70658
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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