|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 194 and 286 of Human CXCR5|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27170 targets CXCR5 in WB applications and shows reactivity with Human samples.
The PA5-27170 immunogen is synthetic peptide corresponding to a region within amino acids 194 and 286 of Human CXCR5.
This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Blr-1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt's lymphoma receptor 1; C-X-C chemokine receptor type 5; CD185; CD185 antigen; chemokine (C-X-C motif) receptor 5; CXC-R5; CXCR-5; GPR9; MDR-15; MDR15; Monocyte-derived receptor 15
Gene Aliases: BLR1; CD185; CXCR5; MDR15
UniProt ID: (Human) P32302
Entrez Gene ID: (Human) 643
Molecular Function: G-protein coupled receptor cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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