|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human CLTR2|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CysLT(2); CysLT-2; CYSLT2; CYSLT2R; CYSLTR2; cysteinyl leukotriene CysLT2 receptor; Cysteinyl leukotriene receptor 2; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; HG57; HGPCR21; HPN321; KPG_011; PSEC0146
Gene Aliases: CYSLT2; CYSLT2R; CYSLTR2; GPCR21; HG57; hGPCR21; HPN321; KPG_011; PSEC0146
UniProt ID: (Human) Q9NS75
Entrez Gene ID: (Human) 57105
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