|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human CYSLTR2 / CYSLT2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Gibbon (95%) Marmoset (80%).
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CYSLT2; CYSLT2R; CysLTR2; cysteinyl leukotriene CysLT2 receptor; Cysteinyl leukotriene receptor 2; G protein-coupled receptor; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; HG57; hGPCR21; HPN321; KPG_011
Gene Aliases: CYSLT2; CYSLT2R; CYSLTR2; GPCR21; HG57; hGPCR21; HPN321; KPG_011; PSEC0146
UniProt ID: (Human) Q9NS75
Entrez Gene ID: (Human) 57105
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