|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 601-652of human CaMKII beta|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody detects endogenous protein at a molecular weight of 50-80 kDa.
Purity is >95% by SDS-PAGE.
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be coexpressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ca++/calmodulin-dependent protein kinase II beta subunit; Ca2+/calmodulin-dependent protein kinase II; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II gamma chain; Calcium/calmodulin-dependent protein kinase type II subunit beta; Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II beta subunit; CaM kinase II subunit beta; CaM kinase II subunit gamma; CaM-kinase II beta chain; caM-kinase II gamma chain; CAM2; CAMK; CaMK II; CAMK-II; CaMK-II subunit beta; CaMK-II subunit gamma; CAMK2; CAMK2B; CAMK2G; CAMKB; CAMKG; proline rich calmodulin-dependent protein kinase
Gene Aliases: CAM2; CAMK; CAMK-II; CAMK2; CAMK2B; Camk2d; CAMK2G; CAMKB; CAMKG; Ck2b
Molecular Function: non-receptor serine/threonine protein kinase
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