|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide K-GDNYQKGIPVETD conjugated to KLH, corresponding to amino acids 362-374 (with a N-terminal added lysine) of Human Caspase 8a (MACH alpha 1).|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-27990 detects Caspase 8 from human samples.
PA1-27990 has been successfully used in Western blot applications.
The PA1-27990 immunogen is: Synthetic peptide: K-GDNYQKGIPVETD conjugated to KLH, corresponding to amino acids 362-374 (with a N-terminal added lysine) of Human Caspase 8a (MACH alpha 1).
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; ini
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; CASP-8; caspase 8, apoptosis-related cysteine peptidase; caspase 8, apoptosis-related cysteine protease; Caspase-8; FADD-homologous ICE/CED-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MACH; MACH-alpha-1/2/3 protein; MACH-beta-1/2/3/4 protein; Mch5; MORT1-associated ced-3 homolog
Gene Aliases: ALPS2B; CAP4; Casp-8; CASP8; FLICE; MACH; MCH5
UniProt ID: (Human) Q14790
Entrez Gene ID: (Human) 841
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