|Immunohistochemistry (Paraffin) (IHC (P))||1:400|
|Western Blot (WB)||1:2000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide made to the C-terminus of mouse Cathepsin E.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage conditions||-20°C or -80°C if preferred|
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Suggested positive control: antigen standard for CTSE (transient overexpression lysate).
Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. It may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cathepsin E; Ctse; EC 126.96.36.199; erythrocyte membrane aspartic proteinase; slow-moving proteinase
Gene Aliases: A430072O03Rik; C920004C08Rik; CATE; CE; CEA; CEB; CTSE; Ctsea
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