|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Full-length human Chk1|
|Storage buffer||PBS, pH 7.2|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-23336 detects Chk1 in Human samples.
MA1-23336 has been successfully used in Western Blot procedures.
MA1-23336 immunogen corresponds to Full-length human Chk1.
Chk1 is a kinase involved in the DNA damage checkpoint response, and can phosphorylate Cdc25C. It is hypothesized that Chk1 induces serine 216 phosphorylation of Cdc25C and subsequent binding negatively regulated Cdc25C, thus preventing it from activating Cdc2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell cycle checkpoint kinase; Checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1 checkpoint homolog; Chk1-S; Serine/threonine-protein kinase Chk1
Gene Aliases: CHEK1; CHK1
UniProt ID: (Human) O14757
Entrez Gene ID: (Human) 1111
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