|Tested Species reactivity||Fruit fly, Human, Bovine|
|Host / Isotype||Goat / IgG|
|Immunogen||Full length native protein (purified) (Cow)|
|Storage buffer||whole serum|
|Contains||15mM sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-28518 detects Clathrin from human, bovine samples.
PA1-28518 has been successfully used in immunocytochemistry applications.
The PA1-28518 immunogen is full length native protein (purified) (Cow)
Membrane vesicle formation is a process required for the endocytosis and biosynthesis of various secreted and membrane bound proteins. Clathrin is a protein which assembles into a polyhedral network on the cell membrane as the membrane invaginates, forming a coated pit which is essential to endocytosis. Clathrin is composed of three polypeptides, a 180 kDa heavy chain and two 32-38 kDa light chains which combine to create a distinct three-legged triskelion. It is this morphology which allows clathrin to form its unique polyhedral network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adapter-related protein complex 1 subunit beta-1; adaptor protein complex AP-1 subunit beta-1; AP-1 complex subunit beta-1; beta-1-adaptin; beta-adaptin 1; beta-prime-adaptin; beta1-adaptin; clathrin assembly protein complex 1 beta large chain; Golgi adaptor HA1/AP1 adaptin beta subunit; plasma membrane adaptor HA2/AP2 adaptor beta subunit
Gene Aliases: ADTB1; AP105A; BAM22; BOS_16712; CLAPB2
UniProt ID: (Human) Q10567
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