|ELISA (ELISA)||0.1-1.0 µg/ml|
|Immunocytochemistry (ICC)||1-5 µg/ml|
|Immunofluorescence (IF)||1-5 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||5-10 µg/ml|
|Immunoprecipitation (IP)||10 µg/test|
|Western Blot (WB)||1-3 µg/ml|
|Flow Cytometry (Flow)||See 1 publications below|
|Western Blot (WB)||See 16 publications below|
|Immunocytochemistry (ICC)||See 6 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 5 publications below|
|Miscellaneous PubMed (MISC)||See 20 publications below|
|Immunohistochemistry (Frozen) (IHC (F))||See 1 publications below|
|Immunohistochemistry (IHC)||See 5 publications below|
|Immunofluorescence (IF)||See 2 publications below|
|Tested Species reactivity||Dog, Human, Mouse, Rat|
|Published species reactivity||Rabbit , Rat , Human , Mouse , Chicken , Rhesus monkey|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide derived from the C-terminal region of the human and mouse claudin-1 proteins|
|Storage buffer||PBS, pH 7.4, with 4.5mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Reactivity has been confirmed with human Caco-2 and canine MDCK cell lysates, mouse kidney and intestinal lysates, frozen mouse intestine (jejunum) tissue, and rat kidney homogenates.
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Claudin-1; CLD1; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1
Gene Aliases: AI596271; CLD1; CLDN1; ILVASC; SEMP1; UNQ481/PRO944
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.