|Immunodiffusion (IDF)||Assay Dependent|
|Tested Species reactivity||Dog, Horse, Cat, Guinea pig, Human, Mouse, Rat|
|Host / Isotype||Sheep / IgG|
|Immunogen||Human 155kDa Factor H, purified from plasma|
|Purification||Ion-exchange chromatography, Ammonium sulfate precipitation|
|Storage buffer||glycine buffered saline, pH 7.4, with 0.01% benzamidine, 0.1% EACA, 1mM EDTA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
This antibody does not react with bovine, chicken, goat, pig or rabbit.
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adrenomedullin binding protein; age-related maculopathy susceptibility 1; AHUS1; ARMD4; ARMS1; beta-1-H-globulin; beta-1H; CFHL3; complement component factor H; Complement factor H; complement factor H related protein 3A4/5G4; complement factor H, isoform b; complement inhibitory factor H; factor H; factor H-like 1; FH; FHL1; H factor 1; H factor 1 (complement); H factor 2 (complement); HF; HF1; HF2; HUS; MGC88246; platelet complement factor H; Protein beta-1-H
Gene Aliases: AHUS1; AMBP1; ARMD4; ARMS1; CFH; CFHL3; FH; FHL1; HF; HF1; HF2; HUS; Mud-1; NOM; Sas-1; Sas1
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