|ELISA (ELISA)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Western Blot (WB)||2 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||See 4 publications below|
|Miscellaneous PubMed (MISC)||See 11 publications below|
|Immunohistochemistry (IHC)||See 7 publications below|
|Western Blot (WB)||See 7 publications below|
|Immunocytochemistry (ICC)||See 10 publications below|
|Immunohistochemistry (Paraffin, Frozen) (IHC (P, F))||See 3 publications below|
|Immunofluorescence (IF)||See 4 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Immunoprecipitation (IP)||See 1 publications below|
|Tested Species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat , Non-human primate , Mouse , Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Synthetic peptide corresponding to a segment of the cytoplasmic loop of rat Connexin-26.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
13-8100 was used in the western blot analysis to successfully detect Connexin 26 in mouse liver homogenate.
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 26kD (connexin 26); 26kDa (connexin 26); beta 2; Connexin 26; Connexin-26; CX26; DFNA3; DFNB1; Gap junction beta-2 protein; gap junction channel protein connexin 26; gap junction membrane channel protein beta 2; gap junction protein; gap junction protein beta 2; gap junction protein, beta 2, 26kDa; GJB2; HID; KID; mutant gap junction protein beta 2; NSRD1; PPK
Gene Aliases: AI325222; Cnx26; CX26; CXN-26; DFNA3; DFNA3A; DFNB1; DFNB1A; Gjb-2; GJB2; HID; KID; NSRD1; PPK
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