|ELISA (ELISA)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:20|
|Western Blot (WB)||1 µg/ml|
|Miscellaneous PubMed (MISC)||See 24 publications below|
|Western Blot (WB)||See 55 publications below|
|Immunohistochemistry (IHC)||See 38 publications below|
|Immunocytochemistry (ICC)||See 18 publications below|
|Immunohistochemistry (Frozen) (IHC (F))||See 17 publications below|
|Immunohistochemistry - Free Floating (IHC (Free))||See 3 publications below|
|Immunofluorescence (IF)||See 7 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 19 publications below|
|Immunoprecipitation (IP)||See 4 publications below|
|Tested Species reactivity||Human, Mouse, Rat|
|Published species reactivity||Tag , Rat , Virus , Bovine , Mouse , Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide corresponding to a segment of the 3rd cytoplasmic domain (C-terminal portion) of rat connexin 43.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
71-0700 was used in the immunofluorescence and western blot analysis to successfully detect Connexin43in mouse heart and thalamus sections and homogenates, respectively.
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha 1 connexin; Connexin 43; Connexin-43; CX43; CXA1; CXN-43; Gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein alpha 1; gap junction protein, alpha 1, 43kDa; GJA1
Gene Aliases: AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin43; CX43; Cx43alpha1; Cxn-43; EKVP; Gja-1; GJA1; GJAL; HLHS1; HSS; Npm1; ODDD; PPKCA
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.